CHM 026 - Organic Chemistry Lecture II
Spring 2002 MW 8:30-9:50 a.m.
Dr. L. Zaikowski
Associate Professor of Chemistry
Office: SCI 113 Office phone: 244-3180
Office Hours:
Mon. 10:00 - 11:30 a.m.
Tues. 10:00 - 10:30 a.m.
Wed. 10:00 - 12:00 a.m.
Required Text:
Organic Chemistry by McMurry 5th ed. (Text and Solutions Manual)
Pushing Electrons by Weeks recommended
Course Objectives:
To provide an
understanding of the fundamental principles, reactions and mechanisms in organic
chemistry. Emphasis is placed on the underlying common themes recurrent in the
study of organic compounds, reaction mechanisms, organic synthesis, and on problem
solving approaches. Attention is given to the important role organic chemistry
plays in biological systems, the environment, and industry.
Requirements:
1. Complete reading assignments
and do the assigned problems for each chapter. These will not be collected,
but you may ask questions about the homework during any class period.
2. Take all quizzes
and exams.
3. Attend class and
actively participate.
Grading Procedure
Each of the three
exams counts 100 points. The quizzes total 70 points, and class participation/attendance
counts up to 20 points. The points are totalled to a maximum of 390 points and
divided by 3.9 to obtain the final grade.
CHM 026 Spring 2002
| Date | Reading | Topic |
| Mon. Feb. 4 | Ch. 15 | Aromaticity |
| Wed. Feb. 6 | 16.1-8 | Chemistry of Benzene: EAS, NAS |
| Mon. Feb. 11 | 16.9-12 | Benzyne, Oxidation/Reduction, Synthesis |
| Wed. Feb. 13 | p. 645-653 and P.E. p. 60-72 | Review |
| Sat. Feb. 15 | 10:00 - 12:00 Explorers Club | Sri Lanka Rainforest: Birthplace of Ecopharmacology, Dr. Andy Greller |
| Mon. Feb. 18 | 17.1-6 | Quiz 1 (50pts: Aromaticity/Rxns. Of Benzene: Ch. 15, 16)Alcohols and Phenols: Nomenclature, sources, properties and preparation |
| Wed. Feb. 20 | 17.7-12 | Rxns. of Alcohols and Phenols |
| Mon. Feb. 25 | Ch. 18 | Ethers & Epoxides, Thiols & Sulfides |
| Wed. Feb. 27 | Review ROH, ROR, RSH | Crown Ethers, Metabolism of Xenobiotics |
| Mon. Mar. 4 | Ch. 24 | Aliphatic and aryl amines: properties, synthesis, and reactions; phase transfer |
| Wed. Mar. 6 | Review | |
| Mon. Mar. 11 | Exam I Ch. 17, 18, 24 | |
| Wed. Mar. 13 | p. 743-752 and19.1-9, 11-16 | Aldehydes and KetonesNucleophilic Addition Rxns. |
| Mon. Mar. 18 | 20.1-921.1-4 | Carboxylic AcidsNucleophilic Acyl Substitution Rxns. |
| Wed. Mar. 20 | 21.5-11 | Esters, Amides, Thiol esters, b-lactams, Acetylcholinesterases |
| Mon. Apr. 1 | 22.1-8 | Carbonyl alpha substitution rxns. |
| Wed. Apr. 3 | MechanismHandout | Mechanisms Workshop/Take Home Quiz |
| Mon. Apr. 8 | 23.1-14 | Mechanisms Take-Home Quiz due(20 pts)Carbonyl Condensation Reactions |
| Wed. Apr. 10 | Review | |
| Mon. Apr. 15 | Exam II Ch. 19-23 | |
| Wed. Apr. 17 | 25.1-6, 7-12 | Carbohydrates |
| Mon. Apr. 22 | 27.1-9 | Lipids |
| Wed. Apr. 24 | 28.1-7 | Heterocycles/AlkaloidsDiels-Alder of azadienes |
| Mon. Apr. 29 | 28.8-17 | Nucleic Acids |
| Wed. May 1 | 26.1,2, 5-9, 11-16 | Proteins/Enzymes |
| Mon. May 6 | 29.1-9 | Metabolic Pathways |
| Wed. May 8 | Review | |
| May | Final Exam: Ch. 25, 26, 27, 28, 29 |
Homework Problems:
Ch. 15: 4, 5, 6, 8, 9, 11,
12, 14, 18, 25, 26, 31, 32, 36, 39, 40, 46
Ch. 16: 4, 5, 6, 7,
8, 9, 11, 13, 14, 15, 16, 23, 27,28, 41, 44, 46, 53
Ch. 17: 2, 3, 4, 5,
10, 13, 30, 31, 36, 41, 44, 51
Ch. 18: 3, 6, 7, 8,
13, 16, 33, 38, 40
Ch. 24: 2, 4, 10,
23, 38, 40, 43
Ch. 19: 2, 6, 7, 9,
10, 13, 29, 34, 36, 39
Ch. 20: 2, 3, 5, 8,
28, 32, 33
Ch. 21: 4, 6, 9, 18,
19, 21, 27, 28, 29, 38, 42, 60
Ch. 22: 1, 2, 3, 7,
10, 20, 21, 40
Ch. 23: 1, 4, 7, 9,
10, 12, 14, 16, 18, 19, 33
Ch. 25: 1, 4, 10,
12, 31, 34, 61
Ch. 27: 4, 5, 15,
16, 23, 37
Ch. 28: 3, 7, 8, 9,
11, 12, 51
Ch. 26: 1, 2, 3, 5,
11, 43, 44, 61
Ch. 29: 3, 5, 6, 7,
9, 10, 13, 14, 15, 27, 40, 41, 46